Symbol
Name
ID

H2-T23
histocompatibility 2, T region locus 23
MGI:95957

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Cerebral hemorrhage	Anemia	Hemolytic anemia	Eosinophilia	Increased T cell count	Leukopenia	Superficial thrombophlebitis	Abnormal platelet aggregation	Thrombocytopenia	Hepatosplenomegaly
Disease(s) Associated with HLA-A	Cerebral hemorrhage	Anemia	Hemolytic anemia	Eosinophilia	Increased T cell count	Leukopenia	Superficial thrombophlebitis	Abnormal platelet aggregation	Thrombocytopenia	Hepatosplenomegaly
Moyamoya disease
pre-eclampsia
Disease(s) Associated with HLA-B
Behcet's disease
sarcoidosis

Mouse Phenotypes

increased mean corpuscular hemoglobin

decreased immature NK cell number

decreased mature NK cell number

decreased NK cell number

increased NK cell number

increased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased gamma-delta T cell number

decreased activated T cell number

abnormal CD8-positive, alpha beta T cell morphology

impaired natural killer cell mediated cytotoxicity

abnormal CD4-positive, alpha-beta T cell physiology

abnormal cytotoxic T cell physiology

abnormal T cell activation

abnormal memory T cell physiology

decreased macrophage nitric oxide production

Availability

Mouse Genotype

H2-D1^bm14/H2-D1^bm14

H2-K1^b-tm1Bpe/H2-K1^b-tm1Bpe

H2-M3^tm1Crw/H2-M3^tm1Crw

H2-M5^{tm1(KOMP)Wtsi}/H2-M5^{tm1(KOMP)Wtsi}

H2-Q10^{tm1.1(KOMP)Mbp}/H2-Q10^{tm1.1(KOMP)Mbp}

H2-T23^tm1Cant/H2-T23^tm1Cant

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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